SCHEMBL8896709

SCHEMBL8896709

O=S(=O)(O)CC(S)C(S)CS(=O)(=O)O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.57
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
LMNA P02545 1/20 0.32
SLC6A6 P31641 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28788387 0.87 SLC22A6 (0.46) SLC22A6PTGS1PDE4A
SCHEMBL8936510 0.83 SLC22A6 (0.48) SLC22A6PTGS1PDE4A
SCHEMBL3944296 0.80
SCHEMBL27821301 0.78
SCHEMBL27415072 0.78
SCHEMBL6772028 0.75
SCHEMBL1425819 0.75
2,3-Dimercapto-1-Propanesulfonic Acid SCHEMBL17744957 0.73
2,3-Dimercapto-1-Propanesulfonic Acid SCHEMBL20483588 0.73
SCHEMBL1578146 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658545-A AIR POLLUTION CONTROL THE REGENTS OF CALIFORNIA (US) 1997-08-19 US disclosed
US-5370849-A Using a water soluble dimercapto compound ligand where the mercapto groups are attached to adjacent carbon atoms and contain a polar functional group THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-12-06 US disclosed