Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PAX3 | P23760 | 1/20 | 0.37 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360865 | 0.84 | ADORA3 (0.42) | TK1TSHR | |
| SCHEMBL5354448 | 0.83 | KDM4E (0.46) | KDM4EPOLA1TAS1R3TAS1R1MEN1 | |
| SCHEMBL29479239 | 0.78 | KDM4E (0.52) | KDM4EPAX3FOXO1POLA1TAS1R3 | |
| SCHEMBL29479241 | 0.78 | KDM4E (0.52) | KDM4EPAX3FOXO1POLA1TAS1R3 | |
| SCHEMBL6365760 | 0.77 | KDM4E (0.51) | KDM4EPOLA1TAS1R3TAS1R1NOS1 | |
| SCHEMBL25968172 | 0.76 | KDM4E (0.52) | KDM4EPOLA1TAS1R3TAS1R1TK1 | |
| SCHEMBL7038608 | 0.76 | POLA1 (0.36) | KDM4EPOLA1TAS1R3TAS1R1TK1 | |
| SCHEMBL3636385 | 0.75 | ADORA3 (0.44) | TK1MEN1TSHRKMT2A | |
| SCHEMBL11051437 | 0.75 | KDM4E (0.45) | KDM4EPOLA1TAS1R3TAS1R1TK1 | |
| SCHEMBL2952014 | 0.75 | SLC28A1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754242-A4 | OLIGONUCLEOTIDE N3'-m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS INC (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0754242-A1 | OLIGONUCLEOTIDE N3'$m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS, INC. (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995025814-A1 | OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | disclosed |