SCHEMBL8896771

SCHEMBL8896771

[CH2]CC(=O)OCC1CCCC1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
SLC1A3 P43003 4/20 0.38
SLC1A2 P43004 4/20 0.38
SLC1A1 P43005 4/20 0.38
MIF P14174 1/20 0.37
PARP15 Q460N3 3/20 0.36
PARP10 Q53GL7 3/20 0.36
POLB P06746 1/20 0.34
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
PARP2 Q9UGN5 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX5 P09917 1/20 0.32
MGLL Q99685 1/20 0.32
NAAA Q02083 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8897162 0.98 LMNA (0.61) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL8894355 0.98 LMNA (0.61) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL8895387 0.98 LMNA (0.61) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL22829337 0.83 LMNA (0.42) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL8894738 0.83 LMNA (0.65) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL27471005 0.82 LMNA (0.81) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL1734351 0.82 LMNA (0.62) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL8893698 0.82 LMNA (0.68) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL8896080 0.82 LMNA (0.68) LMNASLC1A3SLC1A2SLC1A1MIF
SCHEMBL8895826 0.80 LMNA (0.61) LMNASLC1A3SLC1A2SLC1A1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed