Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | MMP3 | P08254 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP7 | P09237 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895791 | 0.98 | IDO1 (0.48) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8895375 | 0.96 | IDO1 (0.49) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8896048 | 0.90 | UTS2R (0.45) | IDO1NPSR1ALDH1A1 | |
| SCHEMBL8896082 | 0.90 | SIGMAR1 (0.41) | IDO1RAB9AMMP2MMP9NPSR1 | |
| SCHEMBL8897207 | 0.90 | ALDH1A1 (0.43) | IDO1NPSR1ALDH1A1ATML3MBTL1 | |
| SCHEMBL8895338 | 0.90 | IDO1 (0.51) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8895816 | 0.90 | NPSR1 (0.47) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8894851 | 0.89 | IDO1 (0.50) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8895709 | 0.89 | IDO1 (0.50) | IDO1RAB9AMMP2MMP1MMP3 | |
| SCHEMBL8896362 | 0.89 | IDO1 (0.50) | IDO1RAB9AMMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |