Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL7530020 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL2943506 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL13140467 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL29525016 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL18139161 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL1172491 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL2952562 | 0.96 | CES2 (0.52) | TSHRCES2EPHX2THRBMEN1 | |
| SCHEMBL11148547 | 0.94 | CES2 (0.50) | TSHRCES2EPHX2THRBMEN1 | |
| Tetraethylene Glycol SCHEMBL3729362 | 0.92 | TSHR (0.65) | TSHRCES2EPHX2THRBMEN1 | |
| Triethylene Glycol SCHEMBL3736596 | 0.92 | TSHR (0.65) | TSHRCES2EPHX2THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3358950-B1 | COMPOSITION FOR ATTRACTING BED BUGS | LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) | 2019-08-28 | — | — | EP | claimed |
| JP-9097572-A | — | — | None | — | — | JP | disclosed |
| US-10653138-B2 | Composition for attracting bed bugs | LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) | 2020-05-19 | — | — | US | disclosed |
| EP-3358950-B1 | COMPOSITION FOR ATTRACTING BED BUGS | LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) | 2019-08-28 | — | — | EP | disclosed |
| WO-2017060682-A1 | COMPOSITION FOR ATTRACTING BED BUGS | LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) | 2017-04-13 | — | — | WO | disclosed |
| JP-H0997572-A | FLUORESCENT SCREEN FOR ELECTRON IRRADIATION | OZAWA RYUJI | 1997-04-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653138-B2 | Composition for attracting bed bugs | UNC119, NISCH, ACHE | TSHR 4047/4885CES2 425/4885EPHX2 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.