Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFPT1 | Q06210 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.39 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895482 | 1.00 | GFPT1 (0.44) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL9570825 | 0.89 | GFPT1 (0.42) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL9570830 | 0.89 | GFPT1 (0.42) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL8648273 | 0.89 | CNR2 (0.47) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL7772177 | 0.89 | CNR2 (0.47) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL29465487 | 0.83 | — | — | |
| SCHEMBL7161352 | 0.82 | CNR2 (0.58) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL17267140 | 0.81 | — | — | |
| SCHEMBL14901 | 0.81 | — | — | |
| SCHEMBL29245397 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618842-A | TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES | LIFEGROUP S.P.A. (IT) | 1997-04-08 | — | — | US | disclosed |