Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFPT1 | Q06210 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570825 | 1.00 | GFPT1 (0.42) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL8897213 | 0.89 | GFPT1 (0.44) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL8895482 | 0.89 | GFPT1 (0.44) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL7890988 | 0.86 | CNR2 (0.50) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL7890992 | 0.86 | CNR2 (0.50) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL28682924 | 0.83 | GFPT1 (0.41) | GFPT1CNR2CNR1PPARGPPARD | |
| SCHEMBL8648273 | 0.79 | CNR2 (0.47) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL7772177 | 0.79 | CNR2 (0.47) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL1516261 | 0.76 | MAP3K7 (0.35) | GFPT1MAP3K7TAB1CNR2CNR1 | |
| SCHEMBL13101467 | 0.74 | DDAH1 (0.36) | GFPT1CNR2CNR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550008-A2 | Use of N-acyl derivatives of aminoalcohols with polycarboxylic acids for the manufacture of a medicament for the treatment of pathologies relating to mast cells | LIFEGROUP S.p.A. (IT) | 1993-07-07 | — | — | EP | disclosed |