Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516007 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL19226967 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL28090516 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL23655744 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL900493 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL24816922 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL19869037 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL8992751 | 0.79 | FUCA1 (0.38) | FUCA1AMY1ACA9CA2 | |
| SCHEMBL8897463 | 0.78 | FUCA1 (0.33) | FUCA1AMY1A | |
| SCHEMBL339343 | 0.77 | L3MBTL1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624909-A | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (e-selectin) and LECAM-1 (l-selectin) | GLYCOMED INCORPORATED (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0691813-A4 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INC (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5519008-A | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) | GLYCOMED INCORPORATED (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0691813-A1 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INCORPORATED (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994005152-A1 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INCORPORATED (US) | 1994-03-17 | — | — | WO | disclosed |