Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093238 | 0.82 | FUCA1 (0.34) | FUCA1AMY1ASTAT3 | |
| SCHEMBL8897216 | 0.78 | FUCA1 (0.36) | FUCA1AMY1A | |
| SCHEMBL8771540 | 0.71 | FUCA1 (0.35) | FUCA1AMY1A | |
| SCHEMBL28305170 | 0.69 | CA9 (0.37) | FUCA1AMY1A | |
| SCHEMBL11883382 | 0.68 | AMY1A (0.43) | FUCA1AMY1ASTAT3 | |
| SCHEMBL21303568 | 0.68 | AMY1A (0.43) | FUCA1AMY1ASTAT3 | |
| SCHEMBL25626385 | 0.68 | AMY1A (0.43) | FUCA1AMY1ASTAT3 | |
| SCHEMBL21754731 | 0.68 | FUCA1 (0.39) | FUCA1AMY1ASTAT3 | |
| SCHEMBL29482063 | 0.68 | AMY1A (0.43) | FUCA1AMY1ASTAT3 | |
| SCHEMBL5670720 | 0.68 | L3MBTL1 (0.36) | FUCA1AMY1ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624909-A | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (e-selectin) and LECAM-1 (l-selectin) | GLYCOMED INCORPORATED (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0691813-A4 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INC (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5519008-A | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) | GLYCOMED INCORPORATED (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0691813-A1 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INCORPORATED (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994005152-A1 | DERIVATIVES OF TRITERPENOID ACIDS AS INHIBITORS OF CELL-ADHESION MOLECULES ELAM-1 (E-SELECTIN) AND LECAM-1 (L-SELECTIN) | GLYCOMED INCORPORATED (US) | 1994-03-17 | — | — | WO | disclosed |