Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847373 | 0.87 | DGKA (0.43) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL1033327 | 0.87 | DGKA (0.64) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL813660 | 0.87 | DGKA (0.58) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL813905 | 0.87 | DGKA (0.58) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL28922182 | 0.85 | DGKA (0.68) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL12200847 | 0.83 | DGKA (0.59) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL813361 | 0.82 | ADRA2A (0.54) | DGKATSHRADRA2AADRA1ADNM1 | |
| SCHEMBL4854701 | 0.82 | DGKA (0.39) | DGKATSHRADRA2AADRA1AALDH1A1 | |
| SCHEMBL2250899 | 0.81 | DGKA (0.69) | DGKATSHRDNM1ALDH1A1MAPT | |
| SCHEMBL128495 | 0.81 | DGKA (0.57) | DGKATSHRADRA2AADRA1ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |