Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894733 | 1.00 | CNR2 (0.51) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11306763 | 0.89 | ALDH1A1 (0.46) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL679131 | 0.89 | ALDH1A1 (0.46) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL679130 | 0.89 | ALDH1A1 (0.46) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9570820 | 0.89 | CNR2 (0.45) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL17197801 | 0.89 | CNR2 (0.50) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9570817 | 0.89 | CNR2 (0.45) | CNR2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL5176320 | 0.80 | — | — | |
| SCHEMBL3676840 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ATAAR1 | |
| SCHEMBL19696572 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618842-A | TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES | LIFEGROUP S.P.A. (IT) | 1997-04-08 | — | — | US | disclosed |