SCHEMBL679131

SCHEMBL679131

O=C(C=CC(=O)NCCO)NCCO

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
CNR2 P34972 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
ITGB2 P05107 2/20 0.39
ICAM1 P05362 2/20 0.39
ITGAL P20701 2/20 0.39
PYGL P06737 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11306763 1.00 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL679130 1.00 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL5175942 0.90 ALDH1A1 (0.56) ALDH1A1KMT2ATAAR1
SCHEMBL3676837 0.90 ALDH1A1 (0.56) ALDH1A1KMT2ATAAR1
SCHEMBL3676840 0.90 ALDH1A1 (0.56) ALDH1A1KMT2ATAAR1
SCHEMBL8894733 0.89 CNR2 (0.51) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL8897538 0.89 CNR2 (0.51) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL25381181 0.88 ALDH1A1 (0.42) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL5055232 0.88 ALDH1A1 (0.38) ALDH1A1KMT2AMAPTMEN1USP2
SCHEMBL5175940 0.88 ALDH1A1 (0.38) ALDH1A1KMT2AMAPTMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270496-A1 Pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system EPITECH GROUP S.R.L. (IT) 2007-11-22 US claimed
EP-1844784-A1 A pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system Epitech Group S.r.l. (IT) 2007-10-17 EP claimed
US-20110288037-A1 Pharmaceutical Composition for the Treatment of Pathologies Caused by the General Response of the Immune System DELLA VALLE FRANCESCO (IT) 2011-11-24 US disclosed
US-20110146516-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-23 US disclosed
US-20110017084-A1 IMMERSION TYPE AUTOMATIC DEVELOPING APPARATUS FOR LITHOGRAPHIC PRINTING PLATE AND AUTOMATIC DEVELOPING METHOD FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110020757-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20070270496-A1 Pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system EPITECH GROUP S.R.L. (IT) 2007-11-22 US disclosed
EP-1844784-A1 A pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system Epitech Group S.r.l. (IT) 2007-10-17 EP disclosed
US-5925678-A ADMINISTERING N,N*-BIS-(2-HYDROXYETHYL)-NONANDIAMIDE LIFEGROUP S.P.A. (IT) 1999-07-20 US disclosed
EP-0804179-B1 USE OF N-ACYL DERIVATIVES OF AMINOALCOHOLS IN THE MANUFACTURE OF A MEDICAMENT FOR PRACTISING NEUROPROTECTIVE ACTION IN NEUROPATHOLOGICAL STATES CONNECTED WITH EXCITOTOXICITY LIFEGROUP SPA (IT) 1999-07-14 EP disclosed
US-5618842-A TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES LIFEGROUP S.P.A. (IT) 1997-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288037-A1 Pharmaceutical Composition for the Treatment of Pathologies Caused by the General Response of the Immune System HCAR2, HCAR1, MYD88 ALDH1A1 824/4885KMT2A 3832/4885MAPT 1479/4885
US-20070270496-A1 Pharmaceutical composition for the treatment of pathologies caused by the general response of the immune system HCAR2, HCAR1, MYD88 ALDH1A1 824/4885KMT2A 3832/4885MAPT 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.