SCHEMBL8897615

SCHEMBL8897615

CCCOCCCN1CCC(O)CC1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.46
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP2D6 P10635 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
HRH3 Q9Y5N1 7/20 0.44
HRH2 P25021 1/20 0.44
HRH1 P35367 1/20 0.44
ACHE P22303 1/20 0.44
GNAI3 P08754 2/20 0.41
GNAO1 P09471 2/20 0.41
GNAI1 P63096 2/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
KCNH2 Q12809 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21738355 0.87 HRH3 (0.46) SPHK1MEN1ALDH1A1CYP2D6RAB9A
SCHEMBL10924938 0.84 HRH3 (0.44) ALDH1A1RAB9AHRH3HRH1GNAI3
SCHEMBL1698806 0.82 SPHK1 (0.57) SPHK1MEN1ALDH1A1CYP2D6RAB9A
SCHEMBL6943025 0.81 GNAI3 (0.62) SPHK1ALDH1A1HRH3HRH2HRH1
SCHEMBL22281941 0.81 CYP2D6 (0.48) SPHK1MEN1ALDH1A1CYP2D6RAB9A
SCHEMBL12717293 0.81 HRH3 (0.47) SPHK1MEN1ALDH1A1CYP2D6RAB9A
SCHEMBL24428779 0.80 HRH3 (0.50) MEN1ALDH1A1CYP2D6KMT2AHRH3
SCHEMBL4250726 0.80 GNAO1 (0.60) SPHK1MEN1ALDH1A1CYP2D6RAB9A
Methane SCHEMBL7423590 0.80 SPHK1 (0.56) SPHK1MEN1ALDH1A1CYP2D6RAB9A
SCHEMBL1891298 0.79 GNAO1 (0.63) SPHK1GNAI3GNAO1GNAI1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0784620-A1 N-SUBSTITUTED PIPERIDINYL BICYCLIC BENZOATE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1997-07-23 EP disclosed
WO-1996010027-A1 N-SUBSTITUTED PIPERIDINYL BICYCLIC BENZOATE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1996-04-04 WO disclosed