Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.41 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | IRS1 | P35568 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895764 | 0.91 | TBXA2R (0.42) | ALDH1A1MMP1MMP13 | |
| SCHEMBL8895561 | 0.90 | TBXAS1 (0.42) | ALDH1A1MMP1MMP13 | |
| SCHEMBL8897202 | 0.90 | TBXAS1 (0.42) | ALDH1A1MMP1MMP13 | |
| SCHEMBL8894976 | 0.88 | TBXA2R (0.42) | ALDH1A1MMP1MMP13 | |
| SCHEMBL8896977 | 0.87 | TBXA2R (0.41) | ALDH1A1MMP1MMP13 | |
| SCHEMBL8896692 | 0.87 | TBXA2R (0.43) | GAAALDH1A1MAPTMMP1MMP13 | |
| SCHEMBL8894954 | 0.86 | TBXA2R (0.46) | GAAALDH1A1NPSR1 | |
| SCHEMBL8896800 | 0.85 | IDO1 (0.46) | GAAALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL8896379 | 0.85 | TBXA2R (0.45) | GAAALDH1A1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL8895261 | 0.85 | TBXA2R (0.45) | GAAALDH1A1NPSR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |