Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897202 | 1.00 | TBXAS1 (0.42) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8895764 | 0.99 | TBXA2R (0.42) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8896977 | 0.97 | TBXA2R (0.41) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8894976 | 0.96 | TBXA2R (0.42) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8896692 | 0.95 | TBXA2R (0.43) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8895621 | 0.94 | IDO1 (0.45) | TBXAS1TBXA2RALDH1A1KDM4EMMP1 | |
| SCHEMBL8896800 | 0.93 | IDO1 (0.46) | TBXAS1TBXA2RALDH1A1KDM4EMMP1 | |
| SCHEMBL8897644 | 0.90 | GAA (0.41) | ALDH1A1MMP1MMP13 | |
| SCHEMBL9230573 | 0.89 | TBXA2R (0.40) | TBXAS1TBXA2RPSEN1PSEN2APH1B | |
| SCHEMBL8895652 | 0.89 | IDO1 (0.52) | ALDH1A1KDM4EMMP1MMP13IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |