Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69796 | 0.83 | ALDH1A1 (0.67) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8896289 | 0.82 | HSD17B10 (0.45) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8854745 | 0.81 | ALDH1A1 (0.65) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9696015 | 0.81 | HSD17B10 (0.58) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9174392 | 0.80 | HSD17B10 (0.47) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11635421 | 0.80 | MEN1 (0.72) | HSD17B10MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23088115 | 0.79 | NR4A1 (0.60) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6915686 | 0.78 | NR4A1 (0.58) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6914514 | 0.78 | NR4A1 (0.58) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6918016 | 0.78 | NR4A1 (0.58) | HSD17B10MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635506-A | ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0660824-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006771-A9 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | — | 1994-06-09 | — | — | WO | disclosed |
| WO-1994006771-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-03-31 | — | — | WO | disclosed |