SCHEMBL69796

SCHEMBL69796

O=C(O)c1cccc2cc3ccccc3c(C(=O)O)c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
HSD17B10 Q99714 2/20 0.67
KDM4E B2RXH2 2/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
CYP1A2 P05177 1/20 0.67
GLA P06280 1/20 0.67
HPGD P15428 1/20 0.67
CYP2C19 P33261 1/20 0.67
NR4A1 P22736 1/20 0.56
NR4A2 P43354 1/20 0.56
NR4A3 Q92570 1/20 0.56
CDC25B P30305 4/20 0.54
PTPN1 P18031 1/20 0.49
ME2 P23368 1/20 0.48
ME1 P48163 1/20 0.48
ME3 Q16798 1/20 0.48
GAA P10253 1/20 0.46
POLB P06746 1/20 0.45
GPR35 Q9HC97 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8854745 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL9696015 0.91 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL580215 0.87 KDM4E (0.59) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL8683969 0.86 PTPN1 (0.55) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL11050089 0.86 NR4A1 (0.56) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL8746215 0.85 KDM4E (0.56) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL9174392 0.83 HSD17B10 (0.47) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL8896289 0.83 HSD17B10 (0.45) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL8897686 0.83 HSD17B10 (0.45) ALDH1A1HSD17B10KDM4EMEN1KMT2A
SCHEMBL27778818 0.83 NR4A1 (0.56) ALDH1A1HSD17B10KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291707-B1 DISSOLVING ORGANIC ACID, OR ITS DERIVATIVE IN A BASE COMPOUND SELECTED FROM OF AMINES AND MORPHOLINES; REMOVING IMPURITIES; RECOVERING ACID OR ITS DERIVATIVE; REMOVING ADSORBED BASE COMPOUND TO OBTAIN PURIFIED ACID OR ITS DERIVATIVE LIN TSONG-DAR VINCENT (US) 2001-09-18 US claimed
US-6392091-B1 None US disclosed
CN-110088169-A Method for preparing polyetherimide 沙特基础工业全球技术有限公司 2019-08-02 CN disclosed
CN-104053724-B Resin composition, laminate, multilayer printed wiring board, multilayer flexible wiring board, and method for producing same 旭化成株式会社 2018-05-08 CN disclosed
CN-105602247-B Resin combination, laminate, multilayer printed circuit board and multi-layer flexible circuit board and its manufacture method 旭化成株式会社 2018-05-08 CN disclosed
CN-104769021-B Flexible device substrate, flexible device and its manufacture method, laminate and its manufacture method and resin combination 旭化成株式会社 2017-10-10 CN disclosed
EP-3053914-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-08-10 EP disclosed
EP-3053914-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-08-10 EP disclosed
US-20160033521-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-02-04 US disclosed
US-20160033521-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME LIGHTSHIP MEDICAL LIMITED (GB) 2016-02-04 US disclosed
US-5207949-A Polyester ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
EP-0536208-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-04-14 EP disclosed
EP-0511412-A1 Polyoxymethylene resin composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-11-04 EP disclosed
US-5143982-A Polyester Random Copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-09-01 US disclosed
WO-1992000281-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-01-09 WO disclosed
EP-0453218-A1 Conductive polyoxymethylene resin composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0004973-B1 THERMOPLASTIC MOULDING COMPOSITIONS ON THE BASIS OF POLYACETALS HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-14 EP disclosed
US-4277577-A IMPROVED IMPACT STRENGTH HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-07 US disclosed
EP-0004973-A1 Thermoplastic moulding compositions on the basis of polyacetals HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-31 EP disclosed
US-4169867-A MOLDING COMPOSITIONS BASED ON OXYMETHYLENE POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160033521-A1 FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME QRFPR, TRPA1, GPR52 ALDH1A1 483/4885HSD17B10 2351/4885KDM4E 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.