Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 19/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889896 | 0.91 | CDK4 (0.34) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL13889498 | 0.88 | PDE9A (0.34) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL12601707 | 0.88 | PDE9A (0.34) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL12601702 | 0.79 | PDE9A (0.33) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL13889500 | 0.79 | PDE9A (0.33) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL889888 | 0.74 | RET (0.37) | — | |
| SCHEMBL13889499 | 0.70 | TK2 (0.40) | CDK4CCND1PDE9APDE1CPDE1B | |
| SCHEMBL889922 | 0.67 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL16417829 | 0.67 | RNASE1 (0.49) | — | |
| SCHEMBL17930897 | 0.67 | RNASE1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431366-B2 | Modified oligonucleotides and applications thereof | APPLIED BIOSYSTEMS, LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110287431-A1 | MODIFIED OLIGONUCLEOTIDES AND APPLICATIONS THEREOF | Life Technologies Corporation (US) | 2011-11-24 | — | — | US | disclosed |