Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 17/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601707 | 1.00 | PDE9A (0.34) | PDE9APDE1CRNASE1PDE1BCDK4 | |
| SCHEMBL12601702 | 0.91 | PDE9A (0.33) | PDE9APDE1CRNASE1PDE1BCDK4 | |
| SCHEMBL13889500 | 0.91 | PDE9A (0.33) | PDE9APDE1CRNASE1PDE1BCDK4 | |
| SCHEMBL889780 | 0.88 | CDK4 (0.35) | PDE9APDE1CPDE1BCDK4CCND1 | |
| SCHEMBL12601708 | 0.80 | TK2 (0.40) | PDE9APDE1CPDE1BCDK4CCND1 | |
| SCHEMBL13889499 | 0.80 | TK2 (0.40) | PDE9APDE1CPDE1BCDK4CCND1 | |
| SCHEMBL889896 | 0.79 | CDK4 (0.34) | PDE9APDE1CPDE1BCDK4CCND1 | |
| SCHEMBL13889497 | 0.74 | POLB (0.38) | — | |
| SCHEMBL12601698 | 0.74 | POLB (0.38) | — | |
| SCHEMBL13166487 | 0.69 | RNASE1 (0.36) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517978-B1 | Modified oligonucleotides and applications thereof | APPLIED BIOSYSTEMS, LLC (US) | 2009-04-14 | — | — | US | disclosed |