Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561761 | 1.00 | KMT2A (0.46) | KMT2ARXFP1KDM4EALDH1A1GAA | |
| SCHEMBL7624265 | 0.74 | TDP1 (0.51) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7624256 | 0.74 | TDP1 (0.51) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7624260 | 0.74 | TDP1 (0.51) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Bromide SCHEMBL8900703 | 0.71 | KMT2A (0.38) | KMT2ARXFP1KDM4EALDH1A1GAA | |
| Bromide SCHEMBL8558814 | 0.71 | KMT2A (0.38) | KMT2ARXFP1KDM4EALDH1A1GAA | |
| SCHEMBL7622254 | 0.68 | ATM (0.39) | KMT2AALDH1A1ROCK2 | |
| SCHEMBL7622250 | 0.68 | ATM (0.39) | KMT2AALDH1A1ROCK2 | |
| SCHEMBL7622258 | 0.68 | ATM (0.39) | KMT2AALDH1A1ROCK2 | |
| SCHEMBL6111134 | 0.67 | KMT2A (0.51) | KMT2ARXFP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |