Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.52 |
| ▸ | AQP1 | P29972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907330 | 1.00 | NPY5R (0.57) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL3946319 | 0.88 | NPY5R (0.72) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL3946322 | 0.88 | NPY5R (0.72) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL8897909 | 0.87 | NPY5R (0.55) | NPY5RADRA2AMCHR1 | |
| SCHEMBL8898947 | 0.83 | TLR9 (0.51) | NPY5RADRA2AMCHR1ALDH1A1TRIM58 | |
| SCHEMBL8907323 | 0.81 | TRIM58 (0.57) | NPY5RADRA2AALDH1A1TRIM58 | |
| SCHEMBL8899155 | 0.81 | TRIM58 (0.57) | NPY5RADRA2AALDH1A1TRIM58 | |
| SCHEMBL13793569 | 0.80 | NPY5R (0.52) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13793523 | 0.80 | NPY5R (0.52) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL3947114 | 0.78 | NPY5R (0.72) | NPY5RADRA2AMCHR1AQP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |