Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM58 | Q8NG06 | 3/20 | 0.57 |
| ▸ | KDM1A | O60341 | 3/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907323 | 1.00 | TRIM58 (0.57) | TRIM58KDM1AEHMT2ALDH1A1MAPK1 | |
| SCHEMBL8898947 | 0.94 | TLR9 (0.51) | TRIM58KDM1AEHMT2ALDH1A1MAPK1 | |
| SCHEMBL8890083 | 0.90 | POLB (0.55) | TRIM58KDM1AEHMT2POLBTOP2A | |
| SCHEMBL8908343 | 0.90 | POLB (0.55) | TRIM58KDM1AEHMT2POLBTOP2A | |
| SCHEMBL8899135 | 0.87 | TRIM58 (0.53) | TRIM58KDM1AEHMT2ALDH1A1MAPK1 | |
| SCHEMBL8901747 | 0.86 | TAAR1 (0.56) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| SCHEMBL8898278 | 0.86 | SOS1 (0.52) | TRIM58ALDH1A1RAD52CASP6KMT2A | |
| SCHEMBL8889084 | 0.85 | CASP6 (0.50) | TRIM58RAD52CASP6KMT2AADRA2A | |
| SCHEMBL8898707 | 0.85 | FLT3 (0.48) | TRIM58POLBTOP2ACASP6SLC2A1 | |
| SCHEMBL8888887 | 0.85 | TLR9 (0.51) | TRIM58KDM1AEHMT2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |