Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898477 | 0.98 | LPAR3 (0.44) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL1835381 | 0.82 | CA2 (0.36) | TSHR | |
| SCHEMBL9623948 | 0.76 | TSHR (0.42) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL1118373 | 0.76 | LPAR3 (0.41) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL34470893 | 0.74 | LPAR3 (0.44) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL1118354 | 0.74 | LPAR3 (0.44) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL17079526 | 0.74 | TSHR (0.46) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL17079524 | 0.74 | TSHR (0.46) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL9046492 | 0.72 | — | — | |
| SCHEMBL18161668 | 0.71 | LPAR3 (0.37) | LPAR3LPAR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691434-A | ALKENYLOXYALKYL-SUBSTITUTED | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |