SCHEMBL17079526

SCHEMBL17079526

C=CCCCCCCCCOC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LPAR3 Q9UBY5 2/20 0.44
LPAR2 Q9HBW0 1/20 0.44
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 3/20 0.35
ABCC4 O15439 1/20 0.35
TRPA1 O75762 2/20 0.33
SLC2A1 P11166 1/20 0.33
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17079524 1.00 TSHR (0.46) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL9623948 0.98 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL12403539 0.91 TSHR (0.42) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL25559091 0.89 TSHR (0.38) TSHRLPAR3LPAR2ALDH1A1LMNA
SCHEMBL4300325 0.80
SCHEMBL12361992 0.80 MAPK1 (0.35) ALDH1A1
SCHEMBL13538316 0.80 MAPK1 (0.35) ALDH1A1
SCHEMBL19193963 0.80 MAPK1 (0.35) ALDH1A1
SCHEMBL27240088 0.80 MAPK1 (0.35) ALDH1A1
SCHEMBL27240036 0.80 MAPK1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts UMICORE AG & CO. KG (DE) 2024-04-16 US disclosed
EP-3116848-B1 PROCESS INVOLVING CROSS METATHESIS OF OLEFINS GIVAUDAN SA (CH) 2023-12-27 EP disclosed
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2022-02-24 US disclosed
US-11161104-B2 Reactions of olefin derivatives in the presence of methathesis catalysts UMICORE AG & CO. KG 2021-11-02 US disclosed
US-20210046466-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2021-02-18 US disclosed
CN-111788189-A Reaction of olefin derivatives in the presence of metathesis catalysts 优美科股份公司及两合公司 2020-10-16 CN disclosed
CN-106103403-B Process comprising cross metathesis of olefins 奇华顿股份有限公司 2020-05-19 CN disclosed
US-20190100504-A1 Process Involving Cross Metathesis of Olefins GIVAUDAN S.A. (CH) 2019-04-04 US disclosed
US-10144720-B2 Process involving cross metathesis of olefins GIVAUDAN S.A. (CH) 2018-12-04 US disclosed
EP-3116848-A1 PROCESS INVOLVING CROSS METATHESIS OF OLEFINS Givaudan S.A. (CH) 2017-01-18 EP disclosed
US-20160368888-A1 Process Involving Cross Metathesis of Olefins GIVAUDAN S.A. (CH) 2016-12-22 US disclosed
WO-2015136093-A1 PROCESS INVOLVING CROSS METATHESIS OF OLEFINS GIVAUDAN SA (CH) 2015-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210046466-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS MDK, MTR, MUSK TSHR 1339/4885LPAR3 4220/4885LPAR2 4130/4885
US-11161104-B2 Reactions of olefin derivatives in the presence of methathesis catalysts MDK, MTR, MUSK TSHR 1339/4885LPAR3 4220/4885LPAR2 4130/4885
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS MDK, MTR, MUSK TSHR 1339/4885LPAR3 4220/4885LPAR2 4130/4885
US-10144720-B2 Process involving cross metathesis of olefins SYMPK, CLK1, MOK TSHR 3793/4885LPAR3 4482/4885LPAR2 3627/4885
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts SYMPK, MDK, HCK TSHR 4295/4885LPAR3 3890/4885LPAR2 3923/4885
US-20190100504-A1 Process Involving Cross Metathesis of Olefins SYMPK, CLK1, MOK TSHR 3793/4885LPAR3 4482/4885LPAR2 3627/4885
US-20160368888-A1 Process Involving Cross Metathesis of Olefins SYMPK, CLK1, MOK TSHR 3793/4885LPAR3 4482/4885LPAR2 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.