Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898141 | 0.92 | MEN1 (0.33) | MEN1KMT2AATMGAATDP1 | |
| SCHEMBL8898413 | 0.82 | KDM4E (0.39) | MEN1KMT2AATMGAATDP1 | |
| SCHEMBL8896377 | 0.82 | LMNA (0.33) | MEN1KMT2AATMGAATDP1 | |
| SCHEMBL8895627 | 0.82 | ATM (0.33) | MEN1KMT2AATM | |
| SCHEMBL8898069 | 0.80 | NCEH1 (0.33) | — | |
| SCHEMBL8898745 | 0.77 | GLA (0.31) | MEN1KMT2AALDH1A1NPSR1KDM4E | |
| SCHEMBL8897692 | 0.72 | PARP1 (0.33) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL5457450 | 0.72 | NCEH1 (0.46) | MEN1KMT2AATMGAATDP1 | |
| SCHEMBL5853744 | 0.71 | LMNA (0.37) | ALDH1A1LMNATSHR | |
| SCHEMBL5853738 | 0.71 | LMNA (0.37) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703091-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |