Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896377 | 0.85 | LMNA (0.33) | KDM4EKMT2AL3MBTL1ATMGAA | |
| SCHEMBL8898063 | 0.82 | MEN1 (0.32) | KDM4EKMT2AL3MBTL1ATMGAA | |
| SCHEMBL8895627 | 0.79 | ATM (0.33) | KMT2AATMMEN1 | |
| SCHEMBL8898141 | 0.79 | MEN1 (0.33) | KDM4EKMT2AL3MBTL1ATMGAA | |
| SCHEMBL20025904 | 0.78 | KDM4E (0.39) | KDM4EKMT2AL3MBTL1ATMGAA | |
| SCHEMBL11235332 | 0.78 | TLR8 (0.38) | KDM4EKMT2AL3MBTL1ATMGAA | |
| SCHEMBL5457450 | 0.77 | NCEH1 (0.46) | KDM4EKMT2AATMGAAALDH1A1 | |
| SCHEMBL8898418 | 0.77 | KDM4E (0.37) | KDM4EKMT2AL3MBTL1NR1I2GAA | |
| SCHEMBL11046112 | 0.76 | KDM4E (0.40) | KDM4EKMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL2126040 | 0.75 | ALDH1A1 (0.43) | KDM4EKMT2AL3MBTL1NR1I2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703091-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |