Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900113 | 0.93 | KDM4E (0.51) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL14340699 | 0.90 | KMT2A (0.49) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL2470451 | 0.84 | KDM4E (0.51) | TSHRALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL6935168 | 0.81 | TSHR (0.47) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL17659280 | 0.79 | PLA2G2A (0.47) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL4408743 | 0.77 | TSHR (0.67) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL9310532 | 0.77 | TSHR (0.50) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL10400378 | 0.76 | KDM4E (0.59) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL7811751 | 0.75 | NPSR1 (0.48) | KMT2ATSHRALDH1A1KDM4EMAPT | |
| SCHEMBL644612 | 0.74 | MAPT (0.60) | KMT2ATSHRALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616779-A | Process for the preparation of 2,5-di-phenylamino-terephthalic acid and its dialkyl esters | HOECHST AG (DE) | 1997-04-01 | — | — | US | disclosed |