Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CCR3 | P51677 | 8/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898838 | 1.00 | THRB (0.64) | THRBHTTCCR3CHRNB2CHRNA4 | |
| SCHEMBL8898840 | 1.00 | THRB (0.64) | THRBHTTCCR3CHRNB2CHRNA4 | |
| SCHEMBL8900776 | 0.87 | THRB (0.53) | THRBHTTCCR3CHRNB2CHRNA4 | |
| SCHEMBL8900764 | 0.87 | THRB (0.53) | THRBHTTCCR3CHRNB2CHRNA4 | |
| SCHEMBL8898607 | 0.78 | HTT (1.00) | THRBHTTCHRNB2CHRNA4KIF11 | |
| SCHEMBL8898611 | 0.78 | HTT (1.00) | THRBHTTCHRNB2CHRNA4KIF11 | |
| SCHEMBL29369556 | 0.78 | HTT (1.00) | THRBHTTCHRNB2CHRNA4KIF11 | |
| SCHEMBL8248041 | 0.78 | HTT (1.00) | THRBHTTCHRNB2CHRNA4KIF11 | |
| Hydrochloric Acid SCHEMBL1271899 | 0.77 | HTT (0.98) | THRBHTTCHRNB2CHRNA4KIF11 | |
| SCHEMBL8898736 | 0.77 | HTT (0.98) | THRBHTTCHRNB2CHRNA4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |