Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.69 |
| ▸ | MERTK | Q12866 | 1/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8890523 | 0.99 | NPY5R (0.72) | NPY5RABCG2MERTKKDM1AKDM4E | |
| SCHEMBL8901666 | 0.88 | ABCG2 (0.71) | NPY5RABCG2KDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8890746 | 0.88 | NPY5R (0.77) | NPY5RABCG2MERTKMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8901465 | 0.87 | ABCG2 (0.70) | NPY5RABCG2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8890705 | 0.86 | NPY5R (0.67) | NPY5RABCG2MERTKKDM4EMEN1 | |
| SCHEMBL2591063 | 0.86 | NPY5R (1.00) | NPY5RABCG2MERTKMEN1TP53 | |
| Hydrochloric Acid SCHEMBL8889951 | 0.85 | NPY5R (0.66) | NPY5RABCG2MERTKKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6039677 | 0.85 | NPY5R (0.96) | NPY5RABCG2KDM4EMEN1TP53 | |
| SCHEMBL2204708 | 0.84 | MERTK (0.60) | NPY5RABCG2MERTKKDM1ASLC2A1 | |
| SCHEMBL31471782 | 0.84 | NPY5R (0.58) | NPY5RABCG2MERTKKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |