Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 12/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144201 | 0.75 | FDPS (0.48) | LMNAFDPSPDE3AADRB3PDE4D | |
| SCHEMBL249600 | 0.71 | KDM4E (0.39) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL10784249 | 0.71 | KDM4E (0.39) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL18149028 | 0.71 | LMNA (0.48) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL6659016 | 0.69 | KDM4E (0.44) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL597134 | 0.69 | LMNA (0.33) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL601974 | 0.69 | — | — | |
| SCHEMBL3365741 | 0.69 | — | — | |
| SCHEMBL27469645 | 0.69 | LMNA (0.45) | LMNAKDM4EMMP2THRBMAPK1 | |
| SCHEMBL1533854 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5678242-A | CONTACTING AQUEOUS SOLUTION OF METAL IONS WITH ONE SIDE OF POROUS MEMBRANE HAVING ORGANIC SOLUBLE COMPLEXING AGENT IN PORES TO EXTRACT METAL IONS, CONTACTING OTHER SIDE WITH AQUEOUS SOLUTION OF SECOND COMPLEXING AGENT TO REMOVE | ARCH DEVELOPMENT CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| US-5332531-A | Complexing | ARCH DEVELOPMENT CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |