Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917005 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2RAB9AACHEGAA | |
| SCHEMBL9527993 | 0.83 | L3MBTL1 (0.68) | HRH3L3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL4093054 | 0.82 | MCHR1 (0.51) | HRH3L3MBTL1CYP3A4SMN1; SMN2RAB9A | |
| SCHEMBL5872163 | 0.82 | L3MBTL1 (0.71) | HRH3L3MBTL1SMN1; SMN2RAB9AACHE | |
| SCHEMBL11323025 | 0.81 | L3MBTL1 (0.51) | HRH3L3MBTL1SMN1; SMN2RAB9AACHE | |
| SCHEMBL3140840 | 0.79 | KMT2A (0.53) | HRH3L3MBTL1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15242991 | 0.79 | L3MBTL1 (0.45) | HRH3L3MBTL1SMN1; SMN2RAB9AACHE | |
| SCHEMBL13946703 | 0.79 | HRH3 (0.54) | HRH3L3MBTL1CYP3A4SMN1; SMN2RAB9A | |
| SCHEMBL4893979 | 0.79 | KMT2A (0.49) | HRH3L3MBTL1SMN1; SMN2RAB9AACHE | |
| SCHEMBL2132367 | 0.78 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2RAB9AACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686607-A | Pyridyl ethylation of lactam derivatives | MERCK & CO., INC. (US) | 1997-11-11 | — | — | US | disclosed |