Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899353 | 1.00 | IDO1 (0.44) | IDO1GRM2KDM1AMAOBMEN1 | |
| SCHEMBL8901640 | 1.00 | IDO1 (0.44) | IDO1GRM2KDM1AMAOBMEN1 | |
| SCHEMBL744186 | 0.78 | MEN1 (0.56) | GRM2MEN1KMT2ALMNATRPV6 | |
| SCHEMBL8900195 | 0.76 | ESR2 (0.38) | GRM2KDM1AMAOBMEN1KMT2A | |
| SCHEMBL22112091 | 0.75 | IDO1 (0.45) | IDO1GRM2MEN1KMT2ANR3C1 | |
| SCHEMBL8897447 | 0.72 | ADRA1A (0.39) | GRM2KDM1AMAOBNR3C1ADRA1A | |
| Hydrochloric Acid SCHEMBL8900277 | 0.70 | GRM2 (0.42) | IDO1GRM2TRPV6NR3C1 | |
| SCHEMBL746858 | 0.70 | GRM2 (0.51) | GRM2MEN1KMT2A | |
| SCHEMBL27533679 | 0.69 | GBA1 (0.57) | IDO1 | |
| Oxalic Acid SCHEMBL8889563 | 0.69 | GRM2 (0.41) | IDO1GRM2KDM1AMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997019923-A1 | CYCLOALKYLMETHYL- AND CYCLOALKYLIDENEMETHYL PYRIDINES, PROCESSES FOR THEIR PRODUCTION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |