Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889654 | 0.86 | ADRA1A (0.36) | ADRA1ANR3C1GRM2 | |
| SCHEMBL8899348 | 0.72 | IDO1 (0.44) | ADRA1AKDM1AMAOBNR3C1GRM2 | |
| SCHEMBL8901640 | 0.72 | IDO1 (0.44) | ADRA1AKDM1AMAOBNR3C1GRM2 | |
| SCHEMBL8899353 | 0.72 | IDO1 (0.44) | ADRA1AKDM1AMAOBNR3C1GRM2 | |
| SCHEMBL744186 | 0.70 | MEN1 (0.56) | GRM2 | |
| SCHEMBL27706106 | 0.70 | CALM1 (0.42) | — | |
| SCHEMBL8900195 | 0.68 | ESR2 (0.38) | ADRA1AKDM1AMAOBGRM2 | |
| SCHEMBL28534739 | 0.66 | DRD2 (0.42) | ADRA1A | |
| SCHEMBL8907545 | 0.66 | ADRA1A (0.40) | ADRA1AKDM1AMAOBNR3C1GRM2 | |
| SCHEMBL7975812 | 0.65 | SRD5A1 (0.37) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997019923-A1 | CYCLOALKYLMETHYL- AND CYCLOALKYLIDENEMETHYL PYRIDINES, PROCESSES FOR THEIR PRODUCTION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |