Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899661 | 1.00 | THRB (0.61) | THRBHTTCTSVCTSLKIF11 | |
| Hydrochloric Acid SCHEMBL8899603 | 0.99 | THRB (0.60) | THRBHTTCTSVCTSLKIF11 | |
| SCHEMBL8898312 | 0.99 | THRB (0.60) | THRBHTTCTSVCTSLKIF11 | |
| Hydrochloric Acid SCHEMBL8899598 | 0.99 | THRB (0.60) | THRBHTTCTSVCTSLKIF11 | |
| Hydrochloric Acid SCHEMBL2031159 | 0.79 | THRB (0.53) | THRBHTTCTSVCTSLKIF11 | |
| SCHEMBL8900933 | 0.78 | HTT (0.40) | THRBHTTCHRNA7CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL8901209 | 0.78 | HTT (0.40) | THRBHTTCHRNA7CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL8901203 | 0.78 | HTT (0.40) | THRBHTTCHRNA7CHRNB2CHRNB4 | |
| SCHEMBL8711612 | 0.76 | THRB (0.47) | THRBHTTCTSVCTSLKIF11 | |
| SCHEMBL8900100 | 0.76 | PSEN1 (0.39) | THRBHTTCHRNA7CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | claimed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |