Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899678 | 1.00 | HTR1A (0.54) | HTR1ADRD2 | |
| SCHEMBL9118060 | 0.78 | HTR1A (0.65) | HTR1ADRD2 | |
| SCHEMBL9118053 | 0.78 | HTR1A (0.65) | HTR1ADRD2 | |
| SCHEMBL8902008 | 0.76 | HTR1A (0.67) | HTR1ADRD2 | |
| SCHEMBL8902000 | 0.76 | HTR1A (0.67) | HTR1ADRD2 | |
| SCHEMBL8808944 | 0.70 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL7884970 | 0.69 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL8810279 | 0.68 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8810282 | 0.68 | HTR1A (1.00) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8901588 | 0.68 | HTR1A (0.97) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482084-B1 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5491236-A | NERVOUS SYTEM DISORDERS | THE UPJOHN COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| WO-1991000856-A2 | (1,2N) AND (3,2N)-CARBOCYCLIC-2-AMINO TETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1991-01-24 | — | — | WO | disclosed |