Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458462 | 0.77 | HTR1A (0.62) | HTR1ADRD2 | |
| SCHEMBL9458475 | 0.77 | HTR1A (0.62) | HTR1ADRD2 | |
| SCHEMBL9458466 | 0.77 | HTR1A (0.62) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458338 | 0.76 | HTR1A (0.61) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458335 | 0.76 | HTR1A (0.61) | HTR1ADRD2 | |
| SCHEMBL8810282 | 0.72 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8810279 | 0.72 | HTR1A (1.00) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899835 | 0.71 | HTR1A (0.98) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8899827 | 0.71 | HTR1A (0.98) | HTR1ADRD2 | |
| SCHEMBL7850563 | 0.71 | HTR1A (0.55) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586525-B1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5486611-A | CENTRAL NERVOUS SYSTEM | THE UPJOHN COMPANY (US) | 1996-01-23 | — | — | US | disclosed |