Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878253 | 0.92 | HMGCR (0.33) | HMGCRCTSADHODH | |
| SCHEMBL8900180 | 0.87 | KMT2A (0.32) | HMGCR | |
| SCHEMBL8876785 | 0.85 | — | — | |
| SCHEMBL8902033 | 0.85 | HMGCR (0.34) | HMGCRCTSADHODH | |
| SCHEMBL8876166 | 0.84 | CTSA (0.33) | HMGCRCTSADHODH | |
| SCHEMBL8878142 | 0.82 | HMGCR (0.35) | HMGCR | |
| SCHEMBL8878790 | 0.82 | HMGCR (0.38) | HMGCR | |
| SCHEMBL8877581 | 0.81 | HMGCR (0.33) | HMGCR | |
| SCHEMBL8877730 | 0.80 | HMGCR (0.38) | HMGCRDHODH | |
| SCHEMBL8877642 | 0.80 | HMGCR (0.35) | HMGCRCTSADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |