Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877642 | 0.93 | HMGCR (0.35) | HMGCRMEN1GAAHPGDKMT2A | |
| SCHEMBL8877698 | 0.90 | HMGCR (0.39) | HMGCRHPGD | |
| SCHEMBL8876166 | 0.85 | CTSA (0.33) | HMGCRCTSADHODH | |
| SCHEMBL8899819 | 0.85 | HMGCR (0.32) | HMGCRCTSADHODH | |
| SCHEMBL8879132 | 0.82 | HMGCR (0.41) | HMGCRHPGD | |
| SCHEMBL8876833 | 0.80 | HMGCR (0.33) | HMGCRCTSADHODH | |
| SCHEMBL8878253 | 0.80 | HMGCR (0.33) | HMGCRMEN1GAAHPGDKMT2A | |
| SCHEMBL8900012 | 0.79 | DHODH (0.36) | DHODH | |
| SCHEMBL8877411 | 0.77 | HMGCR (0.40) | HMGCR | |
| SCHEMBL8902024 | 0.77 | HMGCR (0.38) | HMGCRMEN1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |