Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776058 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL8898042 | 0.97 | SMN1; SMN2 (0.45) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL8900259 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL1629142 | 0.90 | THRA (0.49) | SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL8898916 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL28990186 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL28131034 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL35868 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| SCHEMBL3397043 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 | |
| Propane SCHEMBL27565501 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2MAOBESR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |