Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8905477 | 0.99 | NPY5R (0.40) | NPY5REGFRKDRBRAFTNKS | |
| SCHEMBL8893955 | 0.80 | NPY5R (0.40) | NPY5REGFRKDRTNKSTNKS2 | |
| SCHEMBL8891133 | 0.77 | NPY5R (0.46) | NPY5RKDRTNKSTNKS2PARP2 | |
| SCHEMBL8900353 | 0.77 | NPY5R (0.49) | NPY5RMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL8893944 | 0.76 | KMT2A (0.46) | NPY5RMEN1ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL8905468 | 0.75 | KMT2A (0.45) | NPY5RMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL8890323 | 0.74 | NPY5R (0.45) | NPY5REGFRKDRTNF | |
| Hydrochloric Acid SCHEMBL8890553 | 0.73 | NPY5R (0.44) | NPY5REGFRTNFSLC2A1 | |
| SCHEMBL8900365 | 0.73 | SLC2A1 (0.49) | NPY5RMEN1ALDH1A1KMT2ASLC2A1 | |
| Hydrochloric Acid SCHEMBL8892373 | 0.73 | EGFR (0.49) | EGFRKDRTNKSTNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |