Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283295 | 0.72 | AKR1C3 (0.64) | HPGDTAAR1RAB9AKMT2AMEN1 | |
| SCHEMBL2965106 | 0.69 | MTNR1A (0.61) | TAAR1KMT2AMEN1ALDH1A1 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.69 | TDP1 (0.68) | RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL9175449 | 0.69 | TDP1 (0.54) | KMT2AMEN1ALDH1A1GAAAKR1C3 | |
| SCHEMBL18668830 | 0.69 | ACE (0.55) | KMT2AALDH1A1 | |
| SCHEMBL25310377 | 0.68 | POLB (0.53) | HPGDTAAR1RAB9AKMT2AMEN1 | |
| SCHEMBL22474206 | 0.68 | TDP1 (0.58) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3183513 | 0.68 | TSHR (0.68) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL16203411 | 0.67 | ALDH1A1 (0.56) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL22444688 | 0.67 | ALDH1A1 (0.56) | HPGDRAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691362-A | ANTIHISTAMINES, BRONCHODILATORS, ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL DISORDERS | SCHERING-PLOUGH CORPORATION (US) | 1997-11-25 | — | — | US | disclosed |