Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CTSV | O60911 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899073 | 0.80 | KIF11 (0.53) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL1771140 | 0.78 | AR (0.60) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL4132327 | 0.77 | KIF11 (0.86) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL155013 | 0.76 | GABRA1 (0.70) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL29540314 | 0.76 | GABRA1 (0.70) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL4127278 | 0.74 | KIF11 (1.00) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL27939168 | 0.72 | KIF11 (0.54) | KIF11CA12CA9CTSVCTSL | |
| SCHEMBL8899055 | 0.71 | KIF11 (0.50) | KIF11CA12CA9PARP1ABCC8 | |
| SCHEMBL28207452 | 0.71 | KIF11 (0.50) | KIF11PARP1ABCC8KCNJ11MAPT | |
| SCHEMBL3299928 | 0.71 | KIF11 (0.52) | KIF11CA12CA9PKMGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |