Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585892 | 0.91 | MEN1 (0.77) | MEN1KMT2ANR4A2SMPD1MRGPRX4 | |
| SCHEMBL862870 | 0.90 | MEN1 (0.93) | MEN1KMT2ANR4A2SMPD1MRGPRX4 | |
| SCHEMBL31141980 | 0.90 | MEN1 (0.79) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL1426961 | 0.86 | MEN1 (1.00) | MEN1KMT2ANR4A2SMPD1MRGPRX4 | |
| SCHEMBL18687040 | 0.86 | MEN1 (0.74) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL16320242 | 0.86 | NR4A2 (0.71) | MEN1KMT2ANR4A2MRGPRX4NR4A1 | |
| SCHEMBL28493306 | 0.86 | MEN1 (0.64) | MEN1KMT2ANR4A2SMPD1NR4A1 | |
| SCHEMBL1756343 | 0.85 | NR4A2 (0.81) | NR4A2NR4A1NR4A3FFAR1GSTP1 | |
| SCHEMBL5582767 | 0.85 | NR4A2 (0.81) | NR4A2NR4A1NR4A3FFAR1GSTP1 | |
| SCHEMBL8900334 | 0.85 | SMPD1 (0.60) | MEN1KMT2ANR4A2SMPD1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5521160-A | COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY | HOFFMANN-LA ROCHE INC. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |