Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.81 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.81 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.81 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.73 |
| ▸ | PTGES | O14684 | 1/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.70 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.69 |
| ▸ | RXRA | P19793 | 6/20 | 0.69 |
| ▸ | RXRB | P28702 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.68 |
| ▸ | RXRG | P48443 | 1/20 | 0.63 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756343 | 1.00 | NR4A2 (0.81) | NR4A2NR4A1NR4A3SRD5A2PTGES | |
| SCHEMBL4949143 | 0.95 | NR4A2 (0.90) | NR4A2NR4A1NR4A3SRD5A2PTGES | |
| Hydrochloric Acid SCHEMBL8378883 | 0.93 | NR4A2 (0.87) | NR4A2NR4A1NR4A3SRD5A2PTGES | |
| SCHEMBL18625354 | 0.91 | NR4A2 (0.77) | NR4A2NR4A1NR4A3SRD5A2PTGES | |
| SCHEMBL7539817 | 0.90 | SRD5A2 (0.73) | NR4A2NR4A1NR4A3SRD5A2PTGES | |
| SCHEMBL6830467 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL228477 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL4059143 | 0.90 | NR4A2 (1.00) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL1750167 | 0.90 | NR4A2 (0.86) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL8134318 | 0.89 | NR4A2 (0.85) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
| US-6586475-B1 | 5-chloro-N-(2-N,N-diethylamino)ethyl)-2- methoxy-4-(1-naphthoylamino)benzamide and prodrugs, used for prevention of neurodegenarative diseases such as Alzheimer's disease | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1132376-A1 | BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |
| CN-1082023-A | The medicine and the novel benzoic acid derivative that contain benzoic acid derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1994-02-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | NR4A2 214/4885NR4A1 153/4885NR4A3 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.