Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | STS | P08842 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623091 | 0.89 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11857394 | 0.89 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11857389 | 0.89 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL28068491 | 0.89 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11862021 | 0.89 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11853537 | 0.88 | LMNA (0.71) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL959954 | 0.82 | HSD17B1 (1.00) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL4570835 | 0.82 | HSD17B1 (1.00) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL18658723 | 0.82 | HSD17B1 (1.00) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL15308964 | 0.82 | HSD17B1 (1.00) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656622-A | 15,15-dialkyl-substituted derivatives of estradiol | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |