Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846284 | 0.73 | MAPT (0.43) | MAPTKDM4ENPSR1L3MBTL1MAPK1 | |
| SCHEMBL526301 | 0.70 | PRKAA2 (0.49) | ALDH1A1KMT2AADORA2AHPGDCYP19A1 | |
| SCHEMBL8877091 | 0.69 | PRKAA2 (0.60) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28196237 | 0.68 | MAPT (0.65) | MAPTKDM4ENPSR1L3MBTL1MAPK1 | |
| SCHEMBL28255854 | 0.68 | MEN1 (0.66) | MAPTKDM4ENPSR1L3MBTL1MAPK1 | |
| SCHEMBL4355827 | 0.68 | MAPT (0.65) | MAPTKDM4ENPSR1L3MBTL1MAPK1 | |
| SCHEMBL31291015 | 0.68 | MAPT (0.65) | MAPTKDM4ENPSR1L3MBTL1MAPK1 | |
| SCHEMBL7024221 | 0.68 | MEN1 (0.47) | MAPTKDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8877652 | 0.67 | HMGCR (0.44) | MAPTVCPTOP1ADORA2AADORA1 | |
| SCHEMBL8880672 | 0.67 | MAPT (0.47) | MAPTKDM4EVCPTOP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |