Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533774 | 0.80 | MAPT (0.42) | GID4KDM1ATDP1 | |
| SCHEMBL7480391 | 0.77 | PRCP (0.38) | KDM1ASLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL14931991 | 0.72 | HTR2C (0.46) | KDM1AALDH1A1MEN1KMT2A | |
| SCHEMBL164122 | 0.71 | MEN1 (0.59) | ADRA2CGID4KDM1AMAOAMAOB | |
| SCHEMBL31494195 | 0.71 | MEN1 (0.59) | ADRA2CGID4KDM1AMAOAMAOB | |
| SCHEMBL6181098 | 0.71 | MEN1 (0.59) | ADRA2CGID4KDM1AMAOAMAOB | |
| SCHEMBL3348073 | 0.70 | MEN1 (0.54) | ADRA2CGID4KDM1AMAOAMAOB | |
| SCHEMBL8531187 | 0.70 | ABCC9 (0.34) | HPGD | |
| SCHEMBL4599631 | 0.69 | MEN1 (0.53) | ADRA2CGID4ALDH1A1POLBMEN1 | |
| SCHEMBL8542490 | 0.69 | MEN1 (0.53) | ADRA2CGID4ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |