Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.61 |
| ▸ | ADH1C | P00326 | 2/20 | 0.61 |
| ▸ | ADH1A | P07327 | 2/20 | 0.61 |
| ▸ | ADH7 | P40394 | 2/20 | 0.61 |
| ▸ | ADH4 | P08319 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207500 | 0.88 | — | — | |
| SCHEMBL26876586 | 0.82 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL1608989 | 0.80 | — | — | |
| SCHEMBL8901848 | 0.78 | ADH1B (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL304641 | 0.78 | — | — | |
| SCHEMBL23697411 | 0.77 | ADH1B (0.75) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL1751053 | 0.77 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL12967867 | 0.77 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL8890631 | 0.77 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3030276 | 0.77 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |