Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.38 |
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
| ▸ | ADH7 | P40394 | 4/20 | 0.38 |
| ▸ | ADH1C | P00326 | 3/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899269 | 0.89 | — | — | |
| SCHEMBL3020274 | 0.80 | — | — | |
| SCHEMBL5649841 | 0.80 | ADH1B (0.58) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL4136214 | 0.79 | GNAI3 (0.41) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL8901149 | 0.78 | ADH1B (0.61) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL5646910 | 0.78 | ADH1B (0.61) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL302803 | 0.78 | ADH1B (0.61) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL5651899 | 0.76 | — | — | |
| SCHEMBL17732249 | 0.75 | KDM1A (0.38) | ADH1BADH1AADH7ADH1CADH4 | |
| SCHEMBL3955872 | 0.74 | GNAI3 (0.41) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |