Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8188057 | 0.72 | ABCC8 (0.43) | PDE3BPDE3AABCC8KCNJ11GPBAR1 | |
| SCHEMBL16455584 | 0.68 | PDE3B (0.43) | PDE3BPDE3AABCC8KCNJ11GPBAR1 | |
| SCHEMBL29654696 | 0.67 | PDE3B (0.42) | PDE3BPDE3AABCC8KCNJ11MEN1 | |
| SCHEMBL9135463 | 0.66 | ALDH1A1 (0.52) | KMOMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL24596395 | 0.65 | HCAR2 (0.40) | KDM5AKDM4CHCAR2PKMALDH1A1 | |
| SCHEMBL14844997 | 0.65 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL31505536 | 0.65 | GPBAR1 (0.42) | ABCC8KCNJ11GPBAR1PKMKMO | |
| SCHEMBL17808314 | 0.65 | PDE3B (0.40) | PDE3BPDE3AABCC8KCNJ11GPBAR1 | |
| SCHEMBL8178066 | 0.64 | ABCC8 (0.43) | PDE3BPDE3AABCC8KCNJ11GPBAR1 | |
| SCHEMBL5777624 | 0.63 | PDE3B (0.38) | PDE3BPDE3AABCC8KCNJ11GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9301957-A | — | — | None | — | — | JP | disclosed |
| JP-H09301957-A | PYRIMIDIN-4-ONE DERIVATIVE, ITS USE, PRODUCTION INTERMEDIATE THEREFOR AND PRODUCTION OF THE SAME PRODUCTION INTERMEDIATE | SUMITOMO CHEM CO LTD | 1997-11-25 | — | — | JP | disclosed |